The Dhaka Times Desk A serious snake bite can kill a person if not treated immediately. We all know that. But a new drug for heart attack has been discovered from the poison of that poisonous snake. The researchers said that the heart will be treated from the poison of this snake.
Germany has the highest number of deaths from heart attacks and strokes in the world. Conventional heart medications also have harmful side effects. Doctors and researchers are now scrambling to develop new drugs. Thrombosis or blood clotting is one of the main causes of heart attack or stroke. Medicines that prevent or remove blood clots have many harmful side effects. Frankfurt biochemist Johannes Eble had been looking for an alternative material for a long time. Finally found his trace in snake venom. The poisonous striped viper likes to nest in the trees of eastern Australia. Skin color black, scaly skin. Brian Grigg Fry, a snake researcher from Australia, experienced what the deadly venom of this snake can do.
He said, 'I was unconscious for five minutes after being bitten by this snake. When I regained consciousness, a storm of poison swept through my body. The medicine that was given for this took 18 hours to work. Until then, blood dripped continuously from the bite sites.
Blood clotting in response to snake venom could not heal the injury. Johannes Ebler, a biochemist in Frankfurt, was shocked to hear this news. Perhaps a new anti-clotting drug will be found in snake venom. Snake venom contains thousands of different molecules. Not all are poisonous. Many are toxic when exposed to other substances. According to Johannes Eble, snake venom not only contains components that prevent blood clotting, but some components also help re-clotting. That is, blood clots in the veins due to one type of material, while blood flows to the cells of the body due to another material. As a result, the concentration of blood drops drastically, which is very dangerous. Scientist Able wants to use these elements. In this context, he said, nature took millions of years to create something effective and consistent. That means we have to learn from nature to minimize side effects. Which is lacking in conventional medicine. Finding anti-clotting agents is time-consuming. First, the molecules involved in blood clotting must be found. As the body bleeds from an injury, a type of protein or collagen is produced. Blood clots take new shape and form a mesh. This mesh is what stops the bleeding from the injury.
Snake venom contains a substance that inhibits the production of collagen in the blood. As a result, the blood cannot coagulate and continues to fall. Now the question is how to find the thousands of molecules in snake venom that prevent blood clotting. First, they created artificial collagen-receptor by chemical method. Then he exposed it to snake venom and began looking for the anti-clotting agent. Biochemist Johannes Able thinks the method is very simple. In his words, a lot of fishing. Just like fishing, you have to throw the right bait. A second phase of research begins when some molecules of snake venom accumulate at the artificial receptor.
Mathematicians perform computer experiments by simulating exactly the behavior of the molecules they have discovered. Chemical scientists investigate whether these molecules can be made artificially. New drugs made through these processes require many more tests before they can be marketed. The contribution of biochemist Eble and his colleagues in this field is undeniable. It was only through their tireless efforts that it was possible to find the active ingredients in snake venom.
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